Adding MOTS-C to an AOD 9604 stack targets mitochondrial function and cellular energy metabolism
It is often sold alongside research peptides because it fits the same metabolic research space, but chemically it is closer to a small-molecule drug than to peptides like BPC-157 or semaglutide
Split dosing may help if: single morning dose produces effects that fade by afternoon, you are using higher doses (450-500mcg) where sustained levels may help, or evening administration fits your schedule better than early morning
Two other surrogate markers of B12 deficiency are elevated homocysteine and MCV, although several other nutrient deficiencies can cause these levels to be elevated, so be sure to work with your provider when interpreting any lab test results
Say 2.5mg per injection
Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics
